Aminoaciduria and megaloblastic anaemia.
نویسندگان
چکیده
Urinary amino-acid chromatograms from 23 patients with megaloblastic anaemia have been studied before and after therapy. The most consistent abnormality was an increased taurine or increased taurine/glycine ratio. This was not related directly to deficiency of vitamin B(12) or folic acid or to the degree of anaemia.
منابع مشابه
Aminoaciduria in the megaloblastic anaemias.
One-dimensional chromatography (Dent, 1946) was carried out on morning specimens of urine. Had results from this screening test indicated an excess or abnormal pattern of amino-acids, twodimensional chromatography would have been necessary for the identification of the amino-acids. Seven African women suffering from proven megaloblastic anaemia who were admitted between October, 1954, and Octob...
متن کاملObservations on the aminoaciduria in megaloblastic anaemia.
An abnormal excretion of amino-acids in the urine of patients with Addisonian pernicious anaemia in relapse has been reported by Weaver and Neill (1954), by Keeley and Politzer (1956), and by Crane, Hayes, and de Gruchy (1958). Weaver and Neill (1954) stated that in five patients there was an abnormal excretion of taurine with some over-excretion of lysine, cystine, and leucine, while in anothe...
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It has been shown that the incidence of megaloblastic anaemia in a group of 463 randomly selected pregnant women receiving iron was 12 times as high as in a control group of 235 pregnant women receiving iron and folic acid. The incidence of all types of anaemia in the women receiving iron alone was more than three times the incidence in those having iron and folic acid. Some women who were not ...
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Direct destruction and ineffective erythropoesis does not adequately explain the cause of anaemia in malaria. It is possible that there are more other mechanisms involved besides the causes described till date in malarial anaemia. The effect of NO on erythropoesis and a major haematological abnormality (microcytic/normocytic/megaloblastic picture) can significantly be observed on repeated expos...
متن کاملMegaloblastic Anaemia in Premature Infants.
The common anaemia in premature infants is iron deficiency anaemia, but megaloblastic anaemia can also occur and here we report three such cases. Our interest in megaloblastic anaemia was stimulated by a recent case in which megaloblastic anaemia developed when a low phenylalanine diet was being given for treatment of phenylketonuria (Royston and Parry, 1962). In the discussion of this paper Ro...
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عنوان ژورنال:
- Journal of clinical pathology
دوره 13 شماره
صفحات -
تاریخ انتشار 1960